Glutathione - 1500mg

Glutathione (GSH) — 1500mg | Research Grade

Glutathione (γ-L-glutamyl-L-cysteinyl-glycine; CAS 70-18-8) is an endogenous tripeptide thiol antioxidant present in virtually all mammalian cells. This compound is supplied as a lyophilised powder of confirmed high purity, intended exclusively for qualified researchers conducting in vitro and preclinical laboratory investigations.

Biochemical Profile

• Molecular Formula: C₁₀H₁₇N₃O₆S
• Molecular Weight: 307.32 g/mol
• CAS Number: 70-18-8
• Form: Lyophilised powder
• Purity: >99% (HPLC verified)
• Quantity: 1500mg per vial

Research Context

GSH functions as the primary intracellular antioxidant, participating in redox signalling, xenobiotic detoxification via glutathione S-transferase conjugation, and maintenance of protein thiol homeostasis. It is a substrate for glutathione peroxidase (GPx) in the reduction of hydrogen peroxide and lipid hydroperoxides, and is regenerated from its oxidised form (GSSG) by glutathione reductase in a NADPH-dependent reaction. Research applications include oxidative stress modelling, apoptosis pathway studies, and enzyme kinetics assays.

Specifications

• Appearance: White to off-white lyophilised powder
• Solubility: Soluble in water and dilute aqueous buffers (pH 6–8)
• Storage: −20°C, desiccated, protected from light
• Stability: 24 months from manufacture date under recommended storage conditions
• Packaging: Sealed borosilicate glass vial with aluminium crimp cap

Quality Assurance

Each batch is independently tested by HPLC to confirm identity and purity (>99%). Certificate of Analysis (CoA) available upon request.

⚠ Research Use Only. This product is strictly for in vitro and laboratory research purposes. It is not approved for human or veterinary administration, therapeutic use, diagnostic procedures, or clinical application. Handle in accordance with applicable laboratory safety regulations.